Selected Publications

2013

  • Huang G, Yan H, Ye S, Tong C, Ying QL. STAT3 phosphorylation at tyrosine 705 and serine 727 differentially regulates mouse ES cell fates. Stem Cells. 2013 Dec 3. doi: 10.1002/stem.1609. [Epub ahead of print] PMID: 24302476. [PubMed] [PDF]
  • Kim H, Wu J, Ye S, Tai CI, Zhou X, Yan H, Li P, Pera M, Ying QL. Modulation of β-catenin function maintains mouse epiblast stem cell and human embryonic stem cell self-renewal. Nat Commun. 2013;4:2403. doi: 10.1038/ncomms3403. PMID: 23985566. [PubMed] [PDF]
  • Ye S, Li P, Tong C, Ying QL. Embryonic stem cell self-renewal pathways converge on the transcription factor Tfcp2l1. EMBO J. 2013 Oct 2;32(19):2548-60. doi: 10.1038/emboj.2013.175. PMID: 23942238. [PubMed] [PDF]
  • Tai CI, Ying QL. Gbx2, a LIF/Stat3 target, promotes reprogramming to and retention of the pluripotent ground state. J Cell Sci. 2013 Mar 1;126(Pt 5):1093-8. doi: 10.1242/jcs.118273. Epub 2013 Jan 23. PMID: 23345404. [PubMed] [PDF]

2010

  • Tong C, Li P, Wu NL, Yan Y, Ying QL. Production of p53 gene knockout rats by homologous recombination in embryonic stem cells. Nature. 2010 Sep 9;467(7312):211–3. doi: 10.1038/nature09368. Epub 2010 Aug 11. PMID: 20703227. [PubMed] [PDF]

2008

  • Li P, Tong C, Mehrian-Shai R, Jia L, Wu N, Yan Y, Maxson RE, Schulze EN, Song H, Hsieh CL, Pera MF, Ying QL. Germline competent embryonic stem cells derived from rat blastocysts. Cell. 2008 Dec 26;135(7):1299–310. doi: 10.1016/j.cell.2008.12.006. PMID: 19109898. [PubMed] [PDF]
  • Ying QL, Wray J, Nichols J, Batlle-Morera L, Doble B, Woodgett J, Cohen P, Smith A. The ground state of embryonic stem cell self-renewal. Nature. 2008 May 22;453(7194):519–23. doi: 10.1038/nature06968. PMID: 18497825. [PubMed] [PDF]

2003

  • Ying QL, Nichols J, Chambers I, Smith A. BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3. Cell. 2003 Oct 31;115(3):281–92. PMID: 14636556. [PubMed] [PDF]
  • Ying QL, Stavridis M, Griffiths D, Li M, Smith A. Conversion of embryonic stem cells into neuroectodermal precursors in adherent monoculture. Nat Biotechnol. 2003 Feb;21(2):183–6. Epub 2003 Jan 13. PMID: 12524553. [PubMed] [PDF]

2002

  • Ying QL, Nichols J, Evans EP, Smith AG. Changing potency by spontaneous fusion. Nature. 2002 Apr 4;416(6880):545–8. Epub 2002 Mar 13. PMID: 11932748. [PubMed] [PDF]